Sex-based disparities in outcome in pediatric acute lymphoblastic leukemia: a Children's Oncology Group report.
Sumit GuptaDavid T TeacheyZhiguo ChenKaren R RabinKimberly P DunsmoreEric C LarsenKelly W MaloneyLeonard A MattanoStuart S WinterAndrew J CarrollNyla A HeeremaMichael J BorowitzBrent L WoodWilliam L CarrollElizabeth A RaetzNaomi J WinickMignon L LohStephen P HungerMeenakshi DevidasPublished in: Cancer (2022)
Sex-based disparities in ALL persist, attributable to increased CNS relapses in boys with B-ALL. Studies of potential mechanisms are warranted. Improved strategies to identify and modify treatment for patients at highest risk of CNS relapse may have particular benefit for boys.