Effect of Zinc Supplementation on Altered Calcium Homeostasis, Parathyroid Gland, Bone, and Skeletal Muscle Histology Induced by Subchronic Oral Exposure to Glyphosate-Based Herbicide (GOBARA ® ) in Wistar Rats.

Emmanuel Vandi TizheIkechukwu Onyebuchi IgbokweCelestine Onwu-Ibe NjokwuMohammed Yakasai FatihuUssa Delia TizheNajume Dogon-Giginya Ibrahim

Published in: Clinical pathology (Thousand Oaks, Ventura County, Calif.) (2024)

Subchronic GBH exposure impaired calcium homeostasis observed as hypocalcemia, hypovitaminemia D, and secondary hyperparathyroidism and caused tissue damage in parathyroid gland, bone, and muscle of rats and these were mitigated by zinc chloride pretreatment.

Keyphrases

skeletal muscle
bone mineral density
oxide nanoparticles
bone loss
soft tissue
insulin resistance
bone regeneration
oxidative stress
postmenopausal women
metabolic syndrome
body composition