CoH-catalyzed radical hydroalkylation of alkenes with 1,3-dicarbonyls.

Metal-hydride hydrogen atom transfer (MHAT) catalysis has emerged as a useful reaction platform for alkene hydrofunctionalization with high chemoselectivity and predictable branched selectivity. However, MHAT-mediated hydrofunctionalization involves carbon-carbon bond formation still confined to carbon electrophiles. Here, we describe a mild, general, scalable, and functional group tolerant CoH-catalyzed intermolecular hydroalkylation of alkenes with 1,3-dicarbonyls. This kind of CoH-catalyzed coupling of alkenes with carbon nucleophiles represents an important complement to the arsenal of MHAT-initiated hydrofunctionalization of alkenes.