Assessment of neuropharmacological potential of low molecular weight components extracted from Rhinella schneideri toad poison.
Mateus Amaral BaldoAlexandra Olimpio Siqueira CunhaLívea Dornela GodoyJosé Luiz LiberatoJuliana Sakamoto YonedaEliane Candiani ArantesPietro CiancagliniWagner Ferreira Dos SantosEliane Candiani ArantesPublished in: The journal of venomous animals and toxins including tropical diseases (2019)
LMWF from Rhinella schneideri poison has low molecular weight compounds, which were able to inhibit Na+/K+-ATPase activity, increase the L-glutamate uptake and reduced seizures induced by PTZ and NMDA. These results showed that LMWF is a rich source of components with biological functions of high medical and scientific interest.