Clinical importance of changes in magnetic resonance biomarkers for Duchenne muscular dystrophy.
Rebecca J WillcocksAlison M BarnardMichael J DanielsSean C ForbesWilliam T TriplettJohn F BrandsemaErika L FinangerWilliam D RooneySarah KimDah-Jyuu WangDonovan J LottClaudia R SenesacGlenn A WalterH Lee SweeneyKrista VandenbornePublished in: Annals of clinical and translational neurology (2023)
are reliable and highly responsive to disease progression. The MCID for MR measures is less than or equal to the typical annualized change. These results confirm the suitability of these measures for use in DMD and potentially other muscular dystrophies.