Eco-Friendly Stability-Indicating HPLC Method for Related Compounds in Pemetrexed Ditromethamine (Antineoplastic Agent) for Injection.
Arjuna Rao NekkalapudiSreenivas PippallaSreenivas PippallaPublished in: Journal of AOAC International (2024)
The developed liquid chromatographic method greenness and eco-friendliness were assessed by using (GAPI) green analytical procedure index, (AGREE) analytical greenness tool, and found to be green. Pemetrexed Ditromethamine detoxification procedure also developed to protect from environment pollution.
Keyphrases
- small cell lung cancer
- simultaneous determination
- advanced non small cell lung cancer
- minimally invasive
- ms ms
- liquid chromatography
- heavy metals
- risk assessment
- mass spectrometry
- particulate matter
- high performance liquid chromatography
- ionic liquid
- human health
- ultrasound guided
- solid phase extraction
- health risk assessment
- low cost
- tyrosine kinase