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Inflammatory Biomarkers Do Not Differ Between Persistently Seronegative vs Seropositive People With HIV After Treatment in Early Acute HIV Infection.

Catherine W CaiSuteeraporn PinyakornEugène KroonMark de SouzaDonn J ColbyTippawan PankamSupanit PattanachaiwitSasiwimol UbolyamAdam RupertPerrine LallemandRobin DewarHelene C HighbargerJintanat AnanworanichSandhya VasanIrini Sereti
Published in: Open forum infectious diseases (2020)
Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found similar levels of D-dimer, soluble cluster of differentiation 14, C-reactive protein, and interleukin-6, indicating that seronegativity does not affect chronic inflammation in early treated PWH.
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