Curcumin, demethoxycurcumin, and bisdemethoxycurcumin induced caspase-dependent and -independent apoptosis via Smad or Akt signaling pathways in HOS cells.
Hsiu-Chen HuangHsu-Feng LuYu-Hsuan ChenJui-Chieh ChenWen-Hsiang ChouHsiu-Chen HuangPublished in: BMC complementary medicine and therapies (2020)
The combination of these three compounds could be used as a novel target for the treatment of osteosarcoma.