Preventing Thrombohemorrhagic Complications of Heparinized COVID-19 Patients Using Adjunctive Thromboelastography: A Retrospective Study.
Connor M BunchAnthony V ThomasJohn E StillsonLaura GillespieRashid Z KhanNuha ZackariyaFaadil ShariffMahmoud D Al-FadhlNicolas MjaessPeter D MillerMichael T McCurdyDaniel H FulkersonJoseph B MillerHau C KwaanErnest E MooreHunter B MooreMatthew D NealPeter L MartinMark L KricheffMark M WalshPublished in: Journal of clinical medicine (2021)
Significantly, this study demonstrates the need for a precision-based titration strategy of anticoagulation for hospitalized COVID-19 patients. Since severely ill COVID-19 patients may switch between thrombotic or hemorrhagic phenotypes or express both simultaneously, institutions may reduce these complications by developing their own titration strategy using daily conventional coagulation tests with adjunctive thromboelastography.