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Challenges in the management of metastatic gastrointestinal stromal tumor in a patient with neurofibromatosis type 1: a case report.

B G BharathSameer RastogiShamim AhmedAdarsh Barwad
Published in: Journal of medical case reports (2022)
Our patient had germline NF1 mutation and cutaneous stigmata of neurofibromatosis. Our patient had unicentric gastrointestinal stromal tumor occurring at younger age and involving greater curvature of the stomach, with spindle cell type histology and high-risk features. If gastrointestinal stromal tumor occurs at young age, we should look into neurocutaneous markers.
Keyphrases
  • case report
  • squamous cell carcinoma
  • small cell lung cancer
  • signaling pathway
  • oxidative stress
  • immune response
  • lps induced
  • cell proliferation
  • dna repair
  • nuclear factor