Combination of Goniothalamin and Sol-Gel-Derived Bioactive Glass 45S5 Enhances Growth Inhibitory Activity via Apoptosis Induction and Cell Cycle Arrest in Breast Cancer Cells MCF-7.

Siti Aishah Abu BakarAbdul Manaf AliSiti Noor Fazliah Mohd NoorShahrul Bariyah Sahul HamidNur Asna AzharNoor Muzamil MohamadNor Hazwani Ahmad

Published in: BioMed research international (2022)

The anticancer effect of GTN in MCF-7 cells was improved when combined with BG. The findings provide significant insight into the mechanism of GTN-BG against MCF-7 cells, which can potentially be used as a novel anticancer therapeutic approach.

Keyphrases

cell cycle arrest
breast cancer cells
cell death
pi k akt
induced apoptosis
signaling pathway
oxidative stress
cell proliferation