Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.
Dae-Won LeeSae-Won HanYongjun ChaJeong Mo BaeHwang-Phill KimJaemyun LyuHyojun HanHyoki KimHoon JangDuhee BangIksoo HuhTaesung ParkJae-Kyung WonSeung-Yong JeongKyu Joo ParkGyeong Hoon KangTae-You KimPublished in: Cancer (2017)
A PI3K pathway mutation was associated with better RFS for CRC patients treated with adjuvant chemotherapy, and an RTK-RAS pathway mutation was associated with worse RFS. The significance of the prognostic impact differed according to the tumor location. Cancer 2017;123:3513-23. © 2017 American Cancer Society.