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Prognostic Factors in Japanese EGFR Mutation-Positive Non-Small-Cell Lung Cancer: A Real-World Single-Center Retrospective Cohort Study.

Kenta TakashimaHiroki WakabayashiYu MurakamiAtsuhito SaikiYasuo Matsuzawa
Published in: Drugs - real world outcomes (2024)
The patients who were T790M-positive in the first-line treatment with first or second-generation EGFR-TKIs and were given osimertinib as the second or later line treatment had a better prognosis than the patients who were T790M-negative in the first-line treatment with first or second-generation EGFR-TKIs and could not receive osimertinib.
Keyphrases
  • small cell lung cancer
  • epidermal growth factor receptor
  • prognostic factors
  • tyrosine kinase
  • advanced non small cell lung cancer