Expression of SOX2 and OCT4 in odontogenic cysts and tumors.

Ekarat PhattarataratipTarit PanitkulWatunyoo KhodkaewPattarapong AnupuntanunJirapat JaroonvechatamSirawit Pitarangsikul

Published in: Head & face medicine (2021)

SOX2 is differentially expressed in odontogenic cysts and tumors. This could be related to their diverse cells of origin or stages of histogenesis. The overexpression of SOX2 and OCT4 in OKC indicates the acquired stem-like property. Future studies should investigate whether the overexpression of OCT4 and SOX2 contributes to the aggressive behaviors of the tumors.

Keyphrases

transcription factor
stem cells
optical coherence tomography
diabetic retinopathy
induced apoptosis
cell proliferation
endoplasmic reticulum stress
cell death