A Three-Step Screening Procedure for Early Identification of Children at High Risk of Hemophagocytic Lymphohistiocytosis.
Xun LiHaipeng YanZhenghui XiaoTing LuoLonglong XieYufan YangLing GongZhexuan TangMinghui TangJiaotian HuangXinping ZhangMincui ZhengZhenya YaoPing ZangDesheng ZhuXiulan LuPublished in: Journal of clinical immunology (2023)
A significant proportion of pediatric HLH patients present at the hospital without having all three symptoms: fever, splenomegaly, and cytopenias. Our three-step screening procedure, utilizing commonly available clinical and laboratory parameters, can effectively identify pediatric patients who may be at high risk for HLH.