'Off-the-shelf' allogeneic antigen-specific adoptive T-cell therapy for the treatment of multiple EBV-associated malignancies.
Debottam SinhaSriganesh SrihariKirrliee BeckettLaetitia Le TexierMatthew SolomonArchana PanikkarGeorge R AmbalathingalLea LekieffrePauline CrooksSweera RehanMichelle A NellerCorey SmithRajiv KhannaPublished in: Journal for immunotherapy of cancer (2021)
These findings suggest that restriction switching by sequential infusion of allogeneic T-cell therapies that target EBV through distinct HLA alleles may improve clinical response.