Development of the Patient- and Observer-Reported PRUCISION Instruments to Assess Pruritus and Sleep Disturbance in Pediatric Patients with Cholestatic Liver Diseases.

Chad GwaltneyStephanie BeanMeredith VenerusLisa KarlssonNatalie WarholicLise KjemsPatrick Horn

Published in: Advances in therapy (2022)

Novel PRO and ObsRO PRUCISION instruments were created that evaluate the patient experience of cholestatic pruritus in children with PFIC and other cholestatic liver diseases. The content validity of the PRUCISION instruments is established.

Keyphrases

liver injury
drug induced
liver fibrosis
patient reported outcomes
young adults
case report
atopic dermatitis
physical activity
sleep quality
depressive symptoms