Automated assessment of foot elevation in adults with hereditary spastic paraplegia using inertial measurements and machine learning.
Malte OllenschlagerPatrick HöfnerMartin UllrichFelix KlugeTeresa GreinwalderEvelyn LorisMartin RegensburgerBjoern M EskofierJürgen WinklerHeiko GaßnerPublished in: Orphanet journal of rare diseases (2023)
Here, we show that the present wearable gait analysis system is able to objectively assess foot elevation patterns in HSP. Future studies will aim to improve the granularity for continuous tracking of disease severity and monitoring therapy response of HSP patients in a real-world environment.