Rhodium(I)-Catalyzed Cascade Annulation of 1, n -Diynyl Nitrones to 3,4-Fused Fully Substituted Furans.
Xiangdong YuXiaowen JiDandan ShangLei YuPhilip Wai Hong ChanWei-Dong RaoPublished in: Organic letters (2024)
A method for the assembly of fully substituted furans containing a 3,4-fused 5-8-membered carbocycle, heterocycle, or spirocycle from rhodium(I)-catalyzed and 1,1,1,3,3,3-hexafluoroisopropanol (HFIP)-assisted cascade annulation of 1, n -diynyl nitrones has been developed.
Keyphrases