MSCs-engineered biomimetic PMAA nanomedicines for multiple bioimaging-guided and photothermal-enhanced radiotherapy of NSCLC.
Yipengchen YinYongjing LiSheng WangZiliang DongChao LiangJiaxin SunChangchun WangRong ChaiWeiwei FeiJianping ZhangMing QiLiangzhu FengQin ZhangPublished in: Journal of nanobiotechnology (2021)
These results proved that Cyp-PMAA-Fe@MSCs could realize fluorescence/MRI bimodal imaging, while be used in phototermal-therapy-enhanced radiotherapy, providing desirable nanoplatforms for tumor diagnosis and precise treatment of non-small cell lung cancer.
Keyphrases
- early stage
- mesenchymal stem cells
- locally advanced
- radiation therapy
- radiation induced
- small cell lung cancer
- umbilical cord
- high resolution
- magnetic resonance imaging
- photodynamic therapy
- quantum dots
- single molecule
- drug delivery
- advanced non small cell lung cancer
- fluorescent probe
- squamous cell carcinoma
- living cells
- rectal cancer
- diffusion weighted imaging
- replacement therapy
- fluorescence imaging
- combination therapy
- magnetic resonance
- metal organic framework
- epidermal growth factor receptor