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Propentofylline, phosphodiesterase and adenosine reuptake inhibitor modulates lymphocyte subsets and lymphocyte activity after in-vivo administration in non-immunized and SRBC-immunized mice.

Marianna SzczypkaMagdalena LisAgnieszka Suszko-PawłowskaAleksandra PawlakAngelika SysakBożena Obmińska-Mrukowicz
Published in: The Journal of pharmacy and pharmacology (2017)
Propentofylline administration induced inhibition of thymocyte maturation and an increase in Treg subset that might be beneficial for an inhibition of immune response.
Keyphrases
  • peripheral blood
  • immune response
  • high glucose
  • diabetic rats
  • dendritic cells
  • type diabetes
  • metabolic syndrome
  • toll like receptor
  • adipose tissue
  • inflammatory response
  • skeletal muscle
  • stress induced