Induction of IgG2 and IgG4 B-cell memory following sublingual immunotherapy for ryegrass pollen allergy.

Jorn J Heeringa Craig I McKenzie Nirupama P Varese Mark HewAmy T C M BakxPei Mun Aui Jennifer M Rolland Robyn Elizabeth O'Hehir Menno C van Zelm

Published in: Allergy (2019)

Our data provide evidence for immunological effects of SLIT on B-cell memory. Skewing responses toward IgG2 and IgG4 subclasses might be a mechanism to suppress IgE-mediated allergic responses.

Keyphrases

working memory
allergic rhinitis
electronic health record
machine learning