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Plasma Proteomic Associations With Incident Ischemic Stroke in Older Adults: The Cardiovascular Health Study.

Rizwan KalaniTraci M BartzBruce M PsatyMitchell S V ElkindJames S FloydRobert E GersztenAli ShojaieSusan R HeckbertJoshua C BisThomas R AustinDavid L TirschwellJoseph A C DelaneyW T Longstreth
Published in: Neurology (2023)
In a cohort of older adults, NTproBNP and MMP12 were independently associated with IS risk. We identified plasma proteomic determinants of incident cardioembolic and non-cardioembolic IS and found a novel protein associated with IS risk in those with left atrial dysfunction.
Keyphrases
  • left atrial
  • atrial fibrillation
  • cardiovascular disease
  • physical activity
  • mitral valve
  • left ventricular
  • oxidative stress
  • catheter ablation
  • type diabetes
  • binding protein