National surveillance data analysis of COVID-19 vaccine uptake in England by women of reproductive age.
Laura Ann MageeErika MolteniVicky BowyerJeffrey N BoneHarriet BouldingAsma KhalilHiten D MistryLucilla PostonSergio Alessandro SilverioIngrid WolfeEmma L DuncanPeter von Dadelszennull nullPublished in: Nature communications (2023)
Women of reproductive age are a group of particular concern with regards to vaccine uptake, related to their unique considerations of menstruation, fertility, and pregnancy. To obtain vaccine uptake data specific to this group, we obtained vaccine surveillance data from the Office for National Statistics, linked with COVID-19 vaccination status from the National Immunisation Management Service, England, from 8 Dec 2020 to 15 Feb 2021; data from 13,128,525 such women at population-level, were clustered by age (18-29, 30-39, and 40-49 years), self-defined ethnicity (19 UK government categories), and index of multiple deprivation (IMD, geographically-defined IMD quintiles). Here we show that among women of reproductive age, older age, White ethnicity and being in the least-deprived index of multiple deprivation are each independently associated with higher vaccine uptake, for first and second doses; however, ethnicity exerts the strongest influence (and IMD the weakest). These findings should inform future vaccination public messaging and policy.
Keyphrases
- data analysis
- polycystic ovary syndrome
- pregnancy outcomes
- coronavirus disease
- healthcare
- public health
- sars cov
- mental health
- electronic health record
- quality improvement
- big data
- cervical cancer screening
- emergency department
- type diabetes
- pregnant women
- physical activity
- preterm birth
- smoking cessation
- machine learning
- artificial intelligence
- skeletal muscle
- middle aged