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Patterns of brain metastasis immediately before prophylactic cranial irradiation (PCI): implications for PCI optimization in limited-stage small cell lung cancer.

Xiao ChuShuyan LiBingqing XiaLi ChuXi YangJianjiao NiLiqing ZouYida LiCongying XieJie LinZhengfei Zhu
Published in: Radiation oncology (London, England) (2019)
Our findings suggest that PCI is still of importance in LS-SCLC, and MRI evaluation before PCI is indispensable. Investigations are warranted to explore the possibility of moving PCI up to before CRT completion in LS-SCLC patients with prolonged CRT-D. HA-PCI could be considered to reduce neurotoxicity.
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