Meta-analysis of transcriptomic datasets using benchmark dose modeling shows value in supporting radiation risk assessment.

Vinita ChauhanNadine AdamByron KuoAndrew WilliamsCarole L YaukRuth WilkinsRobert Stainforth

Published in: International journal of radiation biology (2020)

Overall, the results from this work highlight the value of the BMD methodology to derive meaningful outputs that are consistent across different models, provided the studies are conducted using a similar dose-range.

Keyphrases

risk assessment
systematic review
case control
rna seq
meta analyses
single cell
human health