Overcoming effector T cell exhaustion in ovarian cancer ascites with a novel adenovirus encoding for a MUC1 bispecific antibody engager and IL-2 cytokine.

Saru BasnetMirte Van der HeijdenDafne C A QuixabeiraElise JirovecSusanna A M Grönberg-Vähä-KoskelaJames H A ClubbAnna KanervaSanteri PakolaLyna HayboutVictor AriasOtto HemminkiTatiana KudlingSadia ZafarVictor Cervera-CarrasconJoao M SantosAkseli Hemminki

Published in: Molecular therapy : the journal of the American Society of Gene Therapy (2024)

Keyphrases

regulatory t cells
cell free
dendritic cells
type iii
gene therapy
immune response