Distinct influence of different vascular risk factors on white matter brain lesions in multiple sclerosis.

Ruth GeraldesMaciej JuryńczykGiordani Dos PassosAlexander PrichlerKaren ChungMarloes HagensSerena RuggieriElena HuergaJaume Sastre-GarrigaChristian EnzingerDeclan T ChardFrederik BarkhofClaudio GasperiniAlex RoviraGabriele C DeLucaJacqueline Palacenull null

Published in: Journal of neurology, neurosurgery, and psychiatry (2020)

Individual VRF appear to affect MS-specific lesions differently. An increase in MS lesions was mainly seen in smokers; however, this VRF is most likely to be present from onset of MS, and other VRF effects may be partly mitigated by treatment. Our findings support that treating VRF and cessation of smoking may be important in the management of MS.

Keyphrases

multiple sclerosis
white matter
mass spectrometry
ms ms
risk factors
smoking cessation
brain injury
subarachnoid hemorrhage