Subthalamic Nucleus Activity during Cognitive Load and Gait Dysfunction in Parkinson's Disease.

Matthew J GeorgiadesJames M ShineMoran GilatJacqueline McMasterBrian OwlerNeil MahantSimon J G Lewis

Published in: Movement disorders : official journal of the Movement Disorder Society (2023)

These preliminary results reveal a potential neurobiological basis for the interplay between cognitive factors and gait disturbances including freezing in Parkinson's disease, informing development of adaptive deep brain stimulation protocols. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

deep brain stimulation
parkinson disease
obsessive compulsive disorder
genome wide
oxidative stress
cerebral palsy
gene expression
dna methylation