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Subthalamic Nucleus Activity during Cognitive Load and Gait Dysfunction in Parkinson's Disease.

Matthew J GeorgiadesJames M ShineMoran GilatJacqueline McMasterBrian OwlerNeil MahantSimon J G Lewis
Published in: Movement disorders : official journal of the Movement Disorder Society (2023)
These preliminary results reveal a potential neurobiological basis for the interplay between cognitive factors and gait disturbances including freezing in Parkinson's disease, informing development of adaptive deep brain stimulation protocols. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
  • deep brain stimulation
  • parkinson disease
  • obsessive compulsive disorder
  • genome wide
  • oxidative stress
  • cerebral palsy
  • gene expression
  • dna methylation