Integrated metabolomics identifies CYP72A67 and CYP72A68 oxidases in the biosynthesis of Medicago truncatula oleanate sapogenins.

Vered TzinJohn H SnyderDong Sik YangDavid V HuhmanBonnie S WatsonStacy N AllenYuhong TangKarel MiettinenPhilipp ArendtJacob PollierAlain GoossensLloyd W Sumner

Published in: Metabolomics : Official journal of the Metabolomic Society (2019)

The cumulative data support that MtCYP72A68 is a multisubstrate, multifunctional oxidase and MtCYP72A67 is a 2β-hydroxylase, both of which function during the early steps of triterpene-oleanate sapogenin biosynthesis.

Keyphrases

cell wall
mass spectrometry
drug delivery
electronic health record
genome wide
cancer therapy
big data
dna methylation
metal organic framework