Simultaneous Quantification of Vancomycin, Linezolid and Voriconazole in Human Plasma by UHPLC-MS/MS: Application in Therapeutic Drug Monitoring.
Yao LiuYanan LiWenli ChenDandan MingWenji LuoJiabi LiangPublished in: Journal of chromatographic science (2024)
The UHPLC-MS/MS method was established and validated for the simultaneous determination of vancomycin, linezolid and voriconazole in human plasma and successfully applied to routine TDM for individualized treatment.
Keyphrases
- ms ms
- simultaneous determination
- liquid chromatography tandem mass spectrometry
- methicillin resistant staphylococcus aureus
- ultra high performance liquid chromatography
- high performance liquid chromatography
- tandem mass spectrometry
- staphylococcus aureus
- liquid chromatography
- solid phase extraction
- clinical practice
- high resolution mass spectrometry
- replacement therapy
- high resolution