Adult leukoencephalopathies with prominent infratentorial involvement can be caused by Erdheim-Chester disease.

Luisa ChiappariniGiulio CavalliTiziana LangellaAnna VenerandoGiacomo De LucaSergio RaspanteGiorgio MarottaBianca PolloGiuseppe LauriaMaria Giulia CangiSimonetta GereviniAndrea BotturiDavide PareysonLorenzo DagnaEttore Salsano

Published in: Journal of neurology (2017)

Symptoms of PIL can be the only clinical manifestation of ECD. Adult patients with PIL of unknown origin should undergo investigations aimed at unveiling ECD, including bone scintigraphy and whole-body FDG-PET. The early diagnosis allows starting disease-modifying therapies of an otherwise life-threatening disease.

Keyphrases

pet ct
positron emission tomography
pet imaging
computed tomography
young adults
physical activity
soft tissue
bone loss
sleep quality