Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study.
Alexis TabahNiccolò BuettiQuentin StaiqulyStéphane RucklyMurat AkovaAbdullah Tarik AslanMarc LeoneAndrew Conway MorrisMatteo BassettiKostoula ArvanitiJeffrey LipmanRicard FerrerHaibo QiuJosé-Artur PaivaPedro PovoaLiesbet De BusJan J De WaeleFarid ZandShreyas GutteAdel AlsisiKhalid AbidiHendrik BrachtYoshiro HayashiKyeongman JeonMuhammed ElhadiFrançois BarbierJean-François Timsitnull nullPublished in: Intensive care medicine (2023)
HA-BSI was frequently caused by Gram-negative, carbapenem-resistant and DTR pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy. Mortality was high, and at day-28 only a minority of the patients were discharged alive from the hospital. Prevention of antimicrobial resistance and focusing on adequate antimicrobial therapy and source control are important to optimize patient management and outcomes.
Keyphrases
- antimicrobial resistance
- end stage renal disease
- gram negative
- intensive care unit
- newly diagnosed
- chronic kidney disease
- ejection fraction
- healthcare
- prognostic factors
- stem cells
- peritoneal dialysis
- risk factors
- cardiovascular disease
- emergency department
- mesenchymal stem cells
- cardiovascular events
- bone marrow
- case report
- cell therapy
- adipose tissue
- acute respiratory distress syndrome
- smoking cessation