Saccharomyces boulardii alleviates ulcerative colitis carcinogenesis in mice by reducing TNF-α and IL-6 levels and functions and by rebalancing intestinal microbiota.

Chunsaier WangWenbin LiHongying WangYiming MaXinhua ZhaoXudong ZhangHong YangJiaming QianJing Nan Li

Published in: BMC microbiology (2019)

S. boulardii effectively reduced UC carcinogenesis in an AOM/DSS induced mice model. This positive result can likely be attributed to the reduction of TNF-α and IL-6 levels or the blockade of their function combined with alterations to the intestinal microbiota.

Keyphrases

ulcerative colitis
rheumatoid arthritis
high fat diet induced
high glucose
diabetic rats
mouse model
wild type
oxidative stress
metabolic syndrome