Mutation Yield of a Custom 212-Gene Next-Generation Sequencing Panel for Solid Tumors: Clinical Experience of the First 260 Cases Tested Using the JAX ActionSeq™ Assay.
Pavalan SelvamMeng-Chang HsiaoGregory OmerzaDaniel BergeronShannon RoweJasmina UvalicMelissa SoucyMichael PeracchioShelbi BurnsBridgette MeyersMatthew PregoQian NieGuruprasad AnandaHarshpreet ChandokKevin KellyAndrew HesseHoney V ReddiPublished in: Molecular diagnosis & therapy (2021)
This study demonstrates that of the genes with documented involvement in cancer, only a limited number are currently clinically significant from a therapeutic, diagnostic and/or prognostic perspective.