Double-stranded RNA immunohistochemistry as a screening tool for viral encephalitis.
Pardis SabetiNima ShariatzadehAndrei BombinKnarik ArkunSanda AlexandrescuB K Kleinschmidt-DeMastersIsaac H SolomonPublished in: American journal of clinical pathology (2023)
Anti-dsRNA IHC can effectively identify a subset of clinically relevant viral infections but not all. The absence of staining should not exclude cases from mNGS if sufficient clinical and histologic suspicion exists.