The positive predictive value of MOG-IgG testing based on the 2023 diagnostic criteria for MOGAD.
Linda NguyenSumit SinghFabricio S FeltrinLauren M TardoRebekah L ClarkeCynthia X WangBenjamin M GreenbergPublished in: Multiple sclerosis journal - experimental, translational and clinical (2024)
We report a PPV of 78.3% for MOG-IgG testing using the 2023 MOGAD diagnostic criteria. Children had higher PPV and frequency of supporting imaging features. Careful consideration is necessary when assigning patients with no core demyelinating event and low titers a MOGAD diagnosis.