The Role of X Chromosome in Alzheimer's Disease Genetics.

Michael E Belloy Yann Le GuenIlaria StewartJoachim Herz Richard ShervaRui ZhangVictoria C Merritt Matthew S Panizzon Richard L Haugernull nullJohn Michael Gaziano Mark W Logue Valerio Napolioni Michael D Greicius

Published in: medRxiv : the preprint server for health sciences (2024)

regulates pH homeostasis in Golgi secretory compartments and is anticipated to have downstream effects on amyloid beta accumulation. Overall, this study significantly advances our knowledge of AD genetics and may provide novel biological drug targets.

Keyphrases

healthcare
cognitive decline
copy number
dna methylation
endoplasmic reticulum