Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA.

Maorui ZhangYuta FukushimaKosuke NozakiHideyuki NakanishiJia DengNoriyuki WakabayashiKeiji Itaka

Published in: Inflammation and regeneration (2023)

These results demonstrate the feasibility of using mRNA medicines to introduce various therapeutic factors, including transcription factors, into target sites. This study provides valuable information for the development of mRNA therapeutics for tissue engineering.

Keyphrases

tissue engineering
bone regeneration
transcription factor
mesenchymal stem cells
bone marrow
binding protein
small molecule
health information