Chemotherapy-induced cognitive impairment in breast cancer survivors: A systematic review of studies from 2000 to 2021.
Omid AmaniMohammad Ali MazaheriMona Malekzadeh MoghaniFariba ZaraniRasool Hamidi ChoolabiPublished in: Cancer reports (Hoboken, N.J.) (2024)
Chemotherapy, affecting cortical and subcortical brain structures, causes a set of cognitive impairments that can lead to impairments in social responsibility acceptance, daily functioning, and quality of life of women. Therefore, rigorous and extensive research design is required to understand the causes and consequences of CRCI using standardized and sensitive measures of cognitive functions. Specifically, studies comparing the effects of different chemotherapy regimens on cognition and potential mechanisms and/or moderators of CRCI would be instrumental in designing more effective therapy regimens and evaluating the efficacy and cost-effectiveness of cognitive rehabilitation and supportive care programs.
Keyphrases
- chemotherapy induced
- white matter
- cognitive impairment
- healthcare
- locally advanced
- case control
- public health
- polycystic ovary syndrome
- high resolution
- physical activity
- resting state
- mild cognitive impairment
- metabolic syndrome
- risk assessment
- multiple sclerosis
- stem cells
- type diabetes
- pregnant women
- squamous cell carcinoma
- mesenchymal stem cells
- pregnancy outcomes
- human health
- functional connectivity
- radiation therapy
- skeletal muscle
- mass spectrometry
- insulin resistance
- subarachnoid hemorrhage