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Progression of hearing loss after LINAC-based stereotactic radiotherapy for vestibular schwannoma is associated with cochlear dose, not with pre-treatment hearing level.

A van LingeR van OsN HoekstraB HeijmenL StienstraA DallengaJ WolbersA Mendez Romero
Published in: Radiation oncology (London, England) (2018)
We found no significant difference between SRS and FSRT. As the deterioration in hearing after radiotherapy for vestibular schwannoma was associated with the cochlea V90, restricting the V90 may reduce progression of hearing loss. The association between loss of functional hearing and baseline PTA seems to be biased by the use of a categorized variable for hearing loss.
Keyphrases
  • hearing loss
  • early stage
  • locally advanced
  • radiation therapy
  • radiation induced
  • squamous cell carcinoma
  • rectal cancer
  • combination therapy
  • brain metastases
  • smoking cessation