Maternal Stressful Life Events During the Periconceptional Period and Orofacial Clefts: A Systematic Review and Meta-Analysis.

Christina TranAndrew A CrawfordAlexander James HamiltonClare E FrenchYvonne Wren Jonathan R SandyGemma Sharp

Published in: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association (2022)

Limited evidence indicated a weak positive association between maternal stressful life events during the periconceptional period and risk of OFC in the offspring, but further studies with greater consistency in research design are needed.

Keyphrases

birth weight
pregnancy outcomes
high fat diet
type diabetes
metabolic syndrome
physical activity
insulin resistance