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Buyang Huanwu Decoction Promotes Angiogenesis after Cerebral Ischemia by Inhibiting the Nox4/ROS Pathway.

Jian ShenKaiyuan HuangYu ZhuKangli XuKaiyuan HuangJianwei Pan
Published in: Evidence-based complementary and alternative medicine : eCAM (2020)
Our study demonstrates that BYHWD promotes neurological function recovery and increases angiogenesis. BYHWD exerts angiogenic effects against cerebral ischemic injury through the downregulation of Nox4, which results in the reduction of ROS generation.
Keyphrases
  • cerebral ischemia
  • subarachnoid hemorrhage
  • reactive oxygen species
  • brain injury
  • blood brain barrier
  • endothelial cells
  • dna damage
  • cell death
  • vascular endothelial growth factor
  • signaling pathway
  • wound healing