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Intravenous iron for heart failure, iron deficiency definitions, and clinical response: the IRONMAN trial.

John G F ClelandPhilip A KalraPierpaolo PellicoriFraser J GrahamPaul W X FoleyIain B SquirePeter J CowburnAlison SeedAndrew L ClarkBen SzwejkowskiPrithwish BanerjeeJustin CookeMark FrancisPiers CliffordAaron WongColin PetrieJohn J V McMurrayElizabeth A ThomsonKirsty WetherallMichele RobertsonIan FordPaul R Kalranull null
Published in: European heart journal (2024)
This hypothesis-generating analysis suggests that anaemia or TSAT < 20% with ferritin > 100 µg/L might identify patients with heart failure who obtain greater benefit from intravenous iron. This interpretation requires confirmation.
Keyphrases
  • iron deficiency
  • heart failure
  • high dose
  • study protocol
  • clinical trial
  • phase iii
  • left ventricular
  • phase ii
  • atrial fibrillation
  • low dose
  • acute heart failure
  • cardiac resynchronization therapy