CCN6 regulates IGF2BP2 and HMGA2 signaling in metaplastic carcinomas of the breast.
Emily R McMullenMaria E GonzalezStephanie L SkalaMai TranDafydd ThomasSabra I DjomehriBoris BurmanKelley M KidwellCelina G KleerPublished in: Breast cancer research and treatment (2018)
These data shed light into the pathogenesis of metaplastic carcinoma and demonstrate a novel CCN6/IGF2BP2/HMGA2 oncogenic pathway with biomarker and therapeutic implications.