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CCN6 regulates IGF2BP2 and HMGA2 signaling in metaplastic carcinomas of the breast.

Emily R McMullenMaria E GonzalezStephanie L SkalaMai TranDafydd ThomasSabra I DjomehriBoris BurmanKelley M KidwellCelina G Kleer
Published in: Breast cancer research and treatment (2018)
These data shed light into the pathogenesis of metaplastic carcinoma and demonstrate a novel CCN6/IGF2BP2/HMGA2 oncogenic pathway with biomarker and therapeutic implications.
Keyphrases
  • pi k akt
  • binding protein
  • growth hormone
  • electronic health record
  • high grade
  • transcription factor
  • big data
  • signaling pathway
  • cell proliferation
  • data analysis
  • artificial intelligence
  • deep learning