Unintentional ingestion of a high dose of acenocoumarol in a young child.
Martijn R BrandsJelmer SytemaMarinus H van HulstArvid W A KampsPublished in: BMJ case reports (2021)
Acute intoxication with a vitamin K antagonist may cause serious coagulopathy. We report the accidental ingestion of a high dose of acenocoumarol in a young child. Two intravenous administrations of 5 mg of vitamin K, in combination with fast and repeated administration of activated charcoal and sodium sulfate, were sufficient to prevent coagulopathy and related symptoms, despite a confirmed elevated blood acenocoumarol concentration (260 µg/L).