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CPGminer: An Interactive Dashboard to Explore the Genomic Features and Taxonomy of Complete Prokaryotic Genomes.

Jaehyun KimSunghyun YoonSandeep KondakalaSteven L FoleyMark HartDong-Heon BaekWenjun WangSung-Kwan KimJohn B SutherlandSeong-Jae KimOhgew Kweon
Published in: Microorganisms (2023)
Prokaryotes, the earliest forms of life on Earth, play crucial roles in global biogeochemical processes in virtually all ecosystems. The ever-increasing amount of prokaryotic genome sequencing data provides a wealth of information to examine fundamental and applied questions through systematic genome comparison. Genomic features, such as genome size and GC content, and taxonomy-centric genomic features of complete prokaryotic genomes (CPGs) are crucial for various fields of microbial research and education, yet they are often overlooked. Additionally, creating systematically curated datasets that align with research concerns is an essential yet challenging task for wet-lab researchers. In this study, we introduce CPGminer, a user-friendly tool that allows researchers to quickly and easily examine the genomic features and taxonomy of CPGs and curate genome datasets. We also provide several examples to demonstrate its practical utility in addressing descriptive questions.
Keyphrases
  • copy number
  • genome wide
  • healthcare
  • microbial community
  • rna seq
  • gene expression
  • big data
  • quality improvement
  • artificial intelligence
  • low cost