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Development of calculation tool for iodine 131 biodistribution depending on the aerosol particle distribution.

Kazuki IwaokaEliza B EnriquezYuki TamakumaMasahiro HosodaShinji TokonamiChitho P FelicianoReiko Kanda
Published in: Radiation protection dosimetry (2023)
Radiation damage to tissues depends on radiation exposure levels. Therefore, we have studied accurate estimations of radiation exposure levels so far. Recently, we developed a tool that can calculate the respiratory tract deposition of radionuclides based on polydisperse particle size distribution. As a next step, there is a need for a new calculation tool for the biodistribution of radionuclides because a fraction of the radionuclides deposited in the respiratory tract is absorbed into the body. In this study, a calculation tool for iodine 131 biodistribution depending on aerosol size distribution was developed. The developed tool in this study is used with the former tool.
Keyphrases
  • respiratory tract
  • oxidative stress
  • magnetic resonance imaging
  • radiation therapy
  • computed tomography
  • radiation induced
  • iron oxide nanoparticles