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Serum urate-lowering efficacy and safety of tigulixostat in gout patients with hyperuricemia: a randomized, double-blind, placebo-controlled, dose-finding trial (CLUE).

Robert TerkeltaubJisoo LeeJiyoung MinSeonghye ShinKenneth G Saag
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
Tigulixostat significantly lowered sUA levels compared to placebo at all doses used with an acceptable safety profile.
Keyphrases
  • placebo controlled
  • phase iii
  • double blind
  • uric acid
  • phase ii
  • study protocol
  • clinical trial
  • phase ii study
  • metabolic syndrome
  • open label
  • squamous cell carcinoma