Maternal MTHFR 677C>T, 1298A>C gene polymorphisms and risk of offspring aneuploidy.

Olivera MiljanovićSlađana TeofilovMiljana AnđelićZvonko MagićBojana Cikota-Aleksić

Published in: Prenatal diagnosis (2022)

Maternal MTHFR 677C>T gene polymorphism, alone or in combination with another 1298A>C polymorphism, appears to be a substantial risk factor for offspring aneuploidy in Montenegro population, especially for sex chromosome aneuploidies and trisomy 13/18, and among younger women.

Keyphrases

pregnancy outcomes
high fat diet
birth weight
polycystic ovary syndrome
pregnant women
gestational age
adipose tissue
type diabetes
weight gain
gene expression
body mass index
preterm birth